Service technicians forum cobas integra 400 plus service manual roger cantonjos allied hospital supply i need service manual of cobas integra 400 plus. Additional molecular assays for use on the cobas 68008800 systems include. Offering highly efficient workflows from sample processing to result interpretation, the cobas 6800 system puts the future of molecular testing in your hands. Roche cobas 4800 system system manual pdf download. Always read the manufacturers package insert for specific instructions regarding specimen collection. This manual covers the complete cobas 4800 system comprised of the cobas 4800 software, the cobas x 480 instrument used for sample preparation, and the. Roche roche announces launch of cobas hpv on the cobas 6800.
Find out more about the cobas 4800 system, which requires minimal maintenance and eliminates many manual steps for maximum workflow efficiency. Cobas integra 400 plus roche diagnostics india cobas integra 400 plus is a fully automated, random access, sample discrete, multianalyte analyzer. Cobas mira plus manual pdf books reader cobas mira plus manual downloads at download free pdf files,ebooks and documents user s guide block scientific. Enhanced lab efficiency eliminating reagent preparation and manual sample handling contribute to time savings, faster result availability and turnaround time. Cobas 4800 system analytical instruments pdf manual download. Sample id via manual entry, barcode reader or download from host. Dependable performance, dependable results the cobas hpv test runs on the advanced cobas 4800 system, which requires minimal maintenance and eliminates many manual steps for maximum lab efficiency. Evaluation of the cobas 4800 test demonstrated that cobas had a low rate of crossreactivity with lowrisk human papillomavirus lrhpv, a 3. It was designed specifically for ivd and has high performance combined with superior fluorescent signal detection. Manual cobas 4800 malware antivirus software scribd. The cobas 4800 system offers stateoftheart test menu, fully automated sample. Blood screening virology genomicsoncology companion.
If necessary, reboot the cobas 4800 workstation and log into the user defined workflow udf partition on the system. Realtime pcr with digital data capture provides accurate qualitative results with no gray zone. The cobas 4800 system brings flexible sample loading to your fingertips. This table top system employs four different technologies namely. Our broad assay menu is held to the rigorous performance standards you expect from roche, and our real. Handling multiple types of primary and secondary vials in the same run, laboratories can reduce manual effort, improve efficiency and reduce the risk of error, to more efficiently manage daily workflow. Manual or cobas ampliprep instrument cobas taqman 48 analyzer. The cobas 4800 system features stateoftheart, fully automated sample preparation combined with realtime polymerase chain reaction pcr technology for amplification and detection of nucleic acid, plus easytouse software that seamlessly integrates both components. Reduced costs long onboard reagent stability and long calibration intervals. Once the system has booted up, follow the appropriate assay instructions for use for more information on the run setup. The cobas 4800 system features primary tube loading to eliminate manual sample transfer steps. The proprietary amperase enzyme destroys virtually all previously generated amplicon to reduce crosscontamination concerns that can lead to falsepositive results. Fda summary of safety and effectiveness data page 1.
Nov 26, 2017 daily prep and maintenance overview for your cobas 8000 modular analyzer series duration. Roche molecular diagnostics is a business area of roche that develops. Roche molecular diagnostics offers a broad range of assays to detect and quantify viral and bacterial pathogens, in both single and multiplex formats. A cookie is a text file that websites send to a visitors computer or other internetconnected device to uniquely identify the visitors browser or to store information or settings in the browser. Every effort has been made to ensure that all the information contained in this manual is correct at the time of printing. Tips o the system stores only the most recent confirmed messages in the message log. Contact us for more information regarding validation support. Systems with a serial number of 5001 or above are cobas b221 systems. Automatic internal controls minimize the potential for falsenegative results. About roche diagnostics diagnostics strategy and business model.
Own the future of molecular testing designed for high throughput applications such as viral load ivd monitoring, blood screening, microbiology testing and womens health, the cobas 6800 can run up to 384 tests in an 8hour shift1,536 tests in 24 hourswith only 3 user interactions per run and up to 8 hours of walkaway time. Roche cobas analyzers the cobas 4000 analyzer series include the cobas c 311 module for clinical chemistry and the cobas e 411 module for immunoassays. This manual is for users of the cobas c 111 instrument. With key components such as optics, reagents and calibrators taken from larger cobas integra and cobas blood gas systems used in reference labs and hospitals, the cobas c111 system joins a family of analyzers designed to deliver consistent results from the smallest to the largest system. The university of minnesotape riodically refines these laboratory methods.
Software amplilink software is a windowsbased, liscompatible user interface that manages up to 3 cobas taqman 48 analyzers. Fda summary of safety and effectiveness data page 4 temperatures are calculated. If the system is not connected to an lis, the user manually selects the test orders. Roche diagnostics gmbh roche applied science customer support nonnenwald 2 82372 penzberg, germany every effort has been made to ensure that all the information contained in the lightcycler 480 instrument operators manual is correct at the time of printing. Inadequate or inappropriate sample collection, storage, and.
The cobas 4800 system integrates fully automated total nucleic acid isolation directly from primary and secondary sample tubes, automated pcr setup, and realtime pcr. Roche unveils the cobas 6800 and cobas 8800 systems at. Cobas taqman 48 analyzer specifications instrument specifications technology the cobas taqman 48 analyzer is a fully automated amplification and detection system for nucleic acids using 5 nuclease technology. Also, there is a daily pipe that should be run prior to restarting the instrument and the green rack. Accepts 96well plates both from the cobas x 480 sampler and the userprepared, opentype instrument, has six optical channels of detection. User will perform daily routine maintenance and cleaningas required in anufacturers operation and the m. Roche cobas 4800 diagnostic systemyoutube com youtube. Easytolearn software that walks user through the entire setup process. Roche automated solutions provide a continuum of innovation towards fully automated systems with increased flexibility. Advanced results algorithm eliminates the need for manual curve analysis.
The systems also enable up to eight hours cobas 6800 and four hours cobas 8800 of walkaway time with minimal user interaction. Mar 28, 2017 the systems also enable up to eight hours cobas 6800 and four hours cobas 8800 of walkaway time with minimal user interaction. To avoid detection of codon 12 and codon silent mutations no amino acid change, a. Advanced results algorithm eliminates the need for manual curve analysis features and benefits easytolearn and easyto. Sample collection should be performed by specifically trained personnel using the recommended swabs. Doubleclick any message to display the message detail dialog box. Turn on the cobas z 480 analyzer if it is turned off. Systems with a serial number up to 5000 are roche omni s systems. For the exon 19 deletion mutations, sequences ranging from 125 to 141 base pairs are targeted. Handling multiple types of primary and secondary vials in the same run, laboratories can reduce manual effort, improve efficiency and reduce the risk of error, to. By continuing to browse the site you are agreeing to our use of cookies.
An operators manual shall be furnished with each model supplied. The document revision information section is located at the end of this document. View and download roche cobas 4800 system system manual online. Simultaneously detects 14 highrisk hpv types and provides specific genotyping information for hpv type 16 and 18 a qualitative multiplex assay that provides specific genotyping information for hpv types 16 and 18, while concurrently detecting the other 12. Dna sample preparation kit for manual sample preparation and the. The roche molecular systems rms ctnc tests consist of six reagent kits.
Cobas mira system users guide 5 daily startup summary for details see cobas mira maintenance and ise maintenance sections. Cobas taqman 48 analyzer specifications instrument specifications. It is the responsibility of the user to contact the person listed on the title. Roche cobas c 111 community, manuals and specifications. The combination of the two analyzers with cobas it 3000 solution provides true operational integration for small laboratories. Roches remote diagnostics support provides enhanced service and technical support.
This disclosure explains what cookies are and the types of cookies roche dialog uses on its website. Process up to 384 cobas 6800 and 960 cobas 8800 tests in an 8hour shift. Hpv vaginal swab cobas high risk laboratory procedure manual. Summary and explanation roche cell collection medium is used to collect specimens to be tested by molecular pcr tests including the cobas 4800. The cobas egfr mutation test v2 is a realtime pcr test for the qualitative detection of defined mutations of the epidermal growth factor receptor egfr gene in nonsmall cell lung cancer nsclc patients. Roche cobas 4800 system system manual 154 pages software version 2. Cobas mira classic analyzer classic cobas mira s analyzer s. Roche manuals manualslib has more than 65 roche manuals.
Cobas taqman 48 analyzer specifications instrument. Defined egfr mutations are detected using dna isolated from formalinfixed paraffinembedded tumor tissue ffpet or circulatingfree. Furthermore, the cobas z 480 analyzer is manufactured and tested according to the following international standards. Our broad assay menu is held to the rigorous performance standards you expect from roche, and our realtime pcr technology delivers reliable results every time. Daily operation 1 switch on the cobas mira analyzer. Manuals and user guides for roche cobas 4800 system. The cobas 4800 system fully automates sample preparation with realtime. Post launch, the system will support additional assays including hpv, ctng and a utility channel for userdefined aps. Roche cobas c 111big lab analyzer performance designed for small workload labs, the cobas c 111 analyzer is a tabletop system designed to set the next gold st. Log onto amplilink software by entering the assigned user id and password. The cobas 4800 system enables flexible ordering for an expanding, diverse menu of individual, combination or laboratorydeveloped tests. Sep 01, 2015 filmed in antrim, this programme introduces roche diagnostics automated medical sampling system. Verification of cobas 4800 software startup user operator. Fda summary of safety and effectiveness data page 6 primers anneal to the target dna sequences.
The presence of a mutant kras sequence in codons 12 and can be detected when the melting temperatures are within specified ranges. How to do the daily maintenance on the cobas 6000 youtube. Roche roche announces launch of cobas hpv on the cobas. Cobas integra 400 plus service manual service technicians forum. User manual user manual stepbystep manual procedures manual getting started user manual. However, roche diagnostics gmbh reserves the right to make any changes necessary without notice as part of ongoing product development. Installation manual roche cobas 4800 system preface intended use 1 1. Offering highly efficient workflows from sample processing to result interpretation, the cobas 8800 system puts the future of molecular testing in your hands.
This users guide is published by roche diagnostics corporation technical publications. The fully automated cobas 4800 system is comprised of the cobas x 480 instrument and the cobas z 480 analyzer. Daily prep and maintenance overview for your cobas 8000 modular analyzer series duration. Furthermore, the cobas z 480 analyzer is manufactured and tested according to the. Up to 96 test results are available in less than 3. This combination of elements provides true walkaway automation for maximum lab efficiency.
Cobas z 480 pcr analyzer is the latest generation of lightcycler family. Our answers your insights life science research solutions key features and benefits the kras mutation test v2 lsr from roche is an allelespecific, realtime pcr test for the qualitative detection and identification of exon 2, 3, and 4 mutations. In conclusion, the cobas 4800 hpv test demonstrated a greater degree of sensitivity and specificity in detecting hrhpv genotypes than the digene hc2 hrhpv test. Fda summary of safety and effectiveness data page 4 the cobas egfr mutation test v2 kit uses primers that define specific basepair sequences for each of the targeted mutations. Advanced results algorithm eliminates the need for manual curve analysis features and benefits easytolearn and easytouse software intuitive user interface. Roche cell collection medium is designed for the preservation and transport of cells to be used in molecular testing andor for the preparation of cytology slides. The intuitive graphical interface provides all the necessary instructions. You will need alcohol prep pads, lint free gauze, and di water for the daily maintenance.
Always read the manufacturers package insert for specific instructions regarding specimen collection and transport for the type of test kit being used. Intended use the cobas 4800 system is intended to be used as a diagnostic or screening system providing sample preparation, amplification and detection of specific targets from human samples. Filmed in antrim, this programme introduces roche diagnostics automated medical sampling system. If searched for a book roche cobas u411 user manual in pdf form, then you have come on to the right website. Requires roche pdf user manuals, service manuals, operating guides.